KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HBS1L
All Species:
15.76
Human Site:
T221
Identified Species:
31.52
UniProt:
Q9Y450
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y450
NP_001138630.1
684
75473
T221
K
S
A
N
P
P
H
T
I
Q
A
S
E
E
Q
Chimpanzee
Pan troglodytes
XP_001170393
684
75454
T221
K
S
A
N
P
P
H
T
I
Q
A
S
E
E
Q
Rhesus Macaque
Macaca mulatta
XP_001099850
683
75608
T221
K
S
A
N
P
P
L
T
V
Q
A
S
E
E
Q
Dog
Lupus familis
XP_533416
685
75774
T222
K
S
V
L
P
S
H
T
I
Q
T
S
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZS7
682
75082
P217
T
P
K
S
A
L
P
P
P
S
L
Q
T
S
E
Rat
Rattus norvegicus
Q6AXM7
679
74756
P214
T
P
K
S
T
A
H
P
P
S
L
Q
T
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511405
675
74590
S224
E
P
N
V
T
P
T
S
A
R
K
P
G
K
S
Chicken
Gallus gallus
XP_001234091
812
88631
A350
P
A
L
S
S
Q
V
A
Q
V
S
E
E
Q
N
Frog
Xenopus laevis
NP_001085851
678
75254
P222
S
F
Q
N
T
E
E
P
N
S
T
M
T
P
G
Zebra Danio
Brachydanio rerio
NP_955970
653
71635
T214
E
A
T
A
V
P
T
T
E
T
P
S
K
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652729
670
74146
D213
V
D
I
S
A
G
D
D
I
S
R
S
S
A
T
Honey Bee
Apis mellifera
XP_623664
869
97147
D265
S
P
D
S
W
M
I
D
L
N
S
A
L
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
91.8
N.A.
89
88.7
N.A.
84
69.4
75.1
69.3
N.A.
46.9
40.5
N.A.
N.A.
Protein Similarity:
100
99.8
98.6
95.3
N.A.
93.5
93.1
N.A.
90.6
75.8
84.3
80.4
N.A.
65.1
58.5
N.A.
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
0
6.6
N.A.
6.6
6.6
6.6
20
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
13.3
20
N.A.
33.3
33.3
6.6
46.6
N.A.
20
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
25
9
17
9
0
9
9
0
25
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
9
17
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
0
9
9
0
9
0
0
9
42
34
25
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
34
0
0
0
0
0
0
% I
% Lys:
34
0
17
0
0
0
0
0
0
0
9
0
9
17
0
% K
% Leu:
0
0
9
9
0
9
9
0
9
0
17
0
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
34
0
0
0
0
9
9
0
0
0
0
9
% N
% Pro:
9
34
0
0
34
42
9
25
17
0
9
9
0
9
0
% P
% Gln:
0
0
9
0
0
9
0
0
9
34
0
17
0
17
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% R
% Ser:
17
34
0
42
9
9
0
9
0
34
17
50
9
17
17
% S
% Thr:
17
0
9
0
25
0
17
42
0
9
17
0
25
0
9
% T
% Val:
9
0
9
9
9
0
9
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _